京都大学医学部附属病院 脳神経外科

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Clinical activity

1)Cerebral Aneurysm

 The department takes pride in its history and achievements as a pioneer in both microscopic and endovascular surgery for cerebral aneurysms in Japan.
Both the craniotomy group and the endovascular group hold joint conferences to discuss treatment options, considering factors such as the anatomical location and shape of the aneurysm, as well as the risk rates for each treatment method. For unruptured cerebral aneurysms discovered through brain health check-ups or MRA, the treatment policy is based on natural history. For ruptured cerebral aneurysms, we take an urgent and aggressive approach to treatment. We also handle many referral cases of giant aneurysms that are difficult to treat, implementing multidisciplinary treatments using vascular anastomosis. Currently, our department is leading a collaborative multi-center clinical study on unruptured cerebral aneurysms.

2)Cerebral Arteriovenous Malformation (AVM)

 The department has a large number of cases of cerebral arteriovenous malformations (AVMs) referred from across the country, and its achievements are recognized globally.
Treatment options include craniotomy, endovascular embolization, and radiation therapy, with craniotomy being the first choice in our department. Based on extensive experience, including detailed long-term follow-up results, we select the most appropriate treatment for each case. In some cases, a combination of all three treatment methods is used. We are constantly striving to develop safer treatment options. Recently, the introduction of 3T MRI and navigation systems has made it possible to perform surgeries that better preserve brain function.

3)Occlusive Cerebrovascular Disease

 We are actively promoting treatments for the prevention of cerebral infarction and the prevention of recurrence.
For example, in cases of carotid artery stenosis, we select either endarterectomy or stenting procedures based on the individual case to perform carotid artery formation and dilation. Regarding Moyamoya disease (Willis circle occlusion), our department has become a key center nationwide, and we have performed bypass surgery in numerous cases. We are also conducting a multi-center clinical study with other institutions.

4)Brain Tumor

 For malignant brain tumors, we perform resection surgery after brain function mapping, followed by radiation and chemotherapy. Regarding chemotherapy for gliomas, we not only provide standard treatments but also actively explore new therapies for low-grade tumors and recurrent cases. For radiation therapy, we hold joint conferences with the Department of Radiation Oncology to offer multidisciplinary treatment using the latest radiation equipment. Additionally, for tumors located in areas related to language and motor function, we have successfully implemented awake surgery and navigation systems, allowing for highly functional brain-preserving surgeries with excellent outcomes. For pituitary adenomas, we use an improved transsphenoidal approach, enabling minimally invasive surgery with short operative times.

5)Epilepsy and Seizures

 Surgical treatment for epilepsy is considered when seizures are drug-resistant, which is the primary condition for treatment.
Prior to surgery, various tests such as long-term video EEG monitoring, magnetoencephalography (MEG), PET, and MRI are used to precisely localize the epileptic focus. Once the focus is accurately determined, focal resection surgery is performed, leading to favorable treatment outcomes.